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Research interests
Research
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Thesis펼치기
- 랩 온 어 패브릭 : 저가 양산형 천시트를 이용한 혈중암세포 선별에 관한 연구, 2017
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Journal Articles펼치기
- Programmed Death 1 and Cytotoxic T-LymphocyteAssociated Protein 4 Gene Expression in Peripheral Blood Mononuclear Cells Can Serve as Prognostic Biomarkers for Hepatocellular Carcinoma, CANCERS, Vol.16,No.8, 1493, 2024
- Prospective Characterization of Circulating Tumor Cell Kinetics in Patients With Oligometastatic Disease Receiving Definitive Intent Radiation Therapy, JCO PRECISION ONCOLOGY, Vol.7, 2023
- Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment, CANCER LETTERS, Vol.562, 2023
- A high-sensitivity cfDNA capture enables to detect the BRAF V600E mutation in papillary thyroid carcinoma, The Korean Journal of Chemical Engineering, Vol.40,No.2, 429~435, 2023
- Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients, BIOSENSORS & BIOELECTRONICS, Vol.226, 2023
- Dendrimer-Peptide Conjugates for Effective Blockade of the Interactions between SARS-CoV-2 Spike Protein and Human ACE2 Receptor, BIOMACROMOLECULES, 2023
- Recent advances in microfluidic approaches for the isolation and detection of exosomes, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2023
- Prospective Characterization of Circulating Tumor Cell Kinetics in Patients with Locoregional Head and Neck Cancer Receiving Definitive Therapy, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol.114,No.3, E290~E290, 2022
- Bimodal liquid biopsy for cancer immunotherapy based on peptide engineering and nanoscale analysis, BIOSENSORS & BIOELECTRONICS, Vol.213, 2022
- Machine learning algorithm based on dual screening for hepatocellular carcinoma using circulating cell-free DNA and cfDHCC scoring system, JOURNAL OF HEPATOLOGY, Vol.77, S921~S921, 2022
- Prospective characterization of circulating tumor cell kinetics in patients treated with radiation therapy per definitive intent oligometastatic paradigm, JOURNAL OF CLINICAL ONCOLOGY, Vol.40,No.16, 2022
- Machine-Learning-Based Clinical Biomarker Using Cell-Free DNA for Hepatocellular Carcinoma (HCC), CANCERS, Vol.14,No.9, 2022
- Branched, dendritic, and hyperbranched polymers in liquid biopsy device design, WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, Vol.14,No.3, 2022
- Dendrimers for cancer immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response, WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, Vol.14,No.2, 2022
- Hierarchically Multivalent Peptide-Nanoparticle Architectures: A Systematic Approach to Engineer Surface Adhesion, ADVANCED SCIENCE, Vol.9,No.4, 2022
- Cytochalasin B Treatment and Osmotic Pressure Enhance the Production of Extracellular Vesicles (EVs) with Improved Drug Loading Capacity, Nanomaterials, Vol.12,No.1, 2022
- Chemically and Biologically Engineered Bacteria-Based Delivery Systems for Emerging Diagnosis and Advanced Therapy, ADVANCED MATERIALS, Vol.33,No.38, 2021
- Tri-modal liquid biopsy: Combinational analysis of circulating tumor cells, exosomes, and cell-free DNA using machine learning algorithm, CLINICAL AND TRANSLATIONAL MEDICINE, Vol.11,No.8, 2021
- Size-Dependent Drug Loading, Gene Complexation, Cell Uptake, and Transfection of a Novel Dendron-Lipid Nanoparticle for Drug/Gene Co-delivery, BIOMACROMOLECULES, Vol.22,No.9, 3746~3755, 2021
- Enhanced detection of cell-free DNA (cfDNA) enables its use as a reliable biomarker for diagnosis and prognosis of gastric cancer, PLOS ONE, Vol.15,No.12, 2020
- Viable and high-throughput isolation of heterogeneous circulating tumor cells using tapered-slit filters, SENSORS AND ACTUATORS B-CHEMICAL, Vol.321, 2020
- Surface engineering for efficient capture of circulating tumor cells in renal cell carcinoma: From nanoscale analysis to clinical application, BIOSENSORS & BIOELECTRONICS, Vol.162, 2020
- CapioCyte (TM) technology for efficient capture and downstream analysis of circulating tumor cells from renal cell carcinoma, CANCER RESEARCH, Vol.80,No.16, 2020
- An Avidity-Based PD-L1 Antagonist Using Nanoparticle-Antibody Conjugates for Enhanced Immunotherapy, NANO LETTERS, Vol.20,No.7, 4901~4909, 2020
- Immunoavidity-Based Capture of Tumor Exosomes Using Poly(amidoamine) Dendrimer Surfaces, NANO LETTERS, Vol.20,No.8, 5686~5692, 2020
- Nanoparticle Conjugation Stabilizes and Multimerizes beta-Hairpin Peptides To Effectively Target PD-1/PD-L1 beta-Sheet-Rich Interfaces, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol.142,No.4, 1832~1837, 2020
- Multi-modal liquid biopsy platform for cancer screening: screening both cancer-associated rare cells and cancer cell-derived vesicles on the fabric filters for a reliable liquid biopsy analysis, NANO CONVERGENCE, Vol.6,No.1, 2019
- HIGHLY SENSITIVE CIRCULATING CELL-FREE DNA (cfDNA) DETECTION USING POLYDOPAMINE-SILICA HYBRIDS ALLOWS EARLY DIAGNOSIS OF HEPATOCELLULAR CARCINOMA, HEPATOLOGY, Vol.70, 73~74, 2019
- Assessing Changes in Circulating Tumor Cells (CTCs) during Preoperative Chemoradiotherapy for Gastrointestinal Malignancies Using a Nanotechnology-Based CTC Capture System, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol.105,No.1, 113~114, 2019
- Quantification and downstream analysis of circulating tumor cells isolated using CapioCyte (TM) liquid biopsy, CANCER RESEARCH, Vol.79,No.13, 2019
- Post-debulking circulating tumor cell as a poor prognostic marker in advanced stage ovarian cancer A prospective observational study, MEDICINE, Vol.98,No.20, 2019
- Sub-lethal hyperthermia promotes epithelial-to-mesenchymal-like transition of breast cancer cells: implication of the synergy between hyperthermia and chemotherapy, RSC ADVANCES, Vol.9,No.1, 52~57, 2019
- Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?, NANO CONVERGENCE, Vol.5, 2018
- Nano-Based Quantification of Circulating Tumor Cells as a Biomarker of Disease Status in Oligometastatic Patients Following Metastases-Directed Radiation Therapy, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol.102,No.3, 138~139, 2018
- Would antioxidant-loaded nanoparticles present an effective treatment for ischemic stroke?, NANOMEDICINE, Vol.13,No.18, 2327~2340, 2018
- Epithelial and mesenchymal circulating tumor cell isolation and discrimination using dual-immunopatterned device with newly-developed anti-63B6 and anti-EpCAM, SENSORS AND ACTUATORS B-CHEMICAL, Vol.260, 320~330, 2018
- Enhancement of isolation sensitivity for the viable heterogeneous circulating tumor cells swelled by hypo-osmotic pressure, RSC ADVANCES, Vol.7,No.78, 49684~49693, 2017
- Circulating tumor cells in the differential diagnosis of adnexal masses, ONCOTARGET, Vol.8,No.44, 77195~77206, 2017
- High-purity capture and release of circulating exosomes using an exosome-specific dual-patterned immunofiltration (ExoDIF) device, NANOSCALE, Vol.9,No.36, 13495~13505, 2017
- Combined effects of chemotherapy to reduce metastasis caused by insufficient hyperthermia, CANCER RESEARCH, Vol.77, 2017
- Microfluidic-based mechanical phenotyping of cells for the validation of epithelial-to-mesenchymal-like transition caused by insufficient heat treatment, SENSORS AND ACTUATORS B-CHEMICAL, Vol.244, 591~598, 2017
- A multi-staining chip using hydrophobic valves for exfoliative cytology in cancer, JOURNAL OF MICROMECHANICS AND MICROENGINEERING, Vol.27,No.7, 2017
- Polyester fabric sheet layers functionalized with graphene oxide for sensitive isolation of circulating tumor cells, BIOMATERIALS, Vol.125, 1~11, 2017
- Lab on a fabric: Mass producible and low-cost fabric filters for the high throughput viable isolation of circulating tumor cells, BIOSENSORS & BIOELECTRONICS, Vol.91, 747~755, 2017
- Frequency-Dependent Impedance Analysis for Discriminating Cancer and Normal Cells Using Microchamber Array, SENSORS AND MATERIALS, Vol.29,No.3, 293~301, 2017
- A viable circulating tumor cell isolation device with high retrieval efficiency using a reversibly deformable membrane barrier, JOURNAL OF MICROMECHANICS AND MICROENGINEERING, Vol.27,No.2, 2017
- Dual-patterned immunofiltration (DIF) device for the rapid efficient negative selection of heterogeneous circulating tumor cells, LAB ON A CHIP, Vol.16,No.24, 4759~4769, 2016
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Books
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Book Chapters
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Patents펼치기
- 미세유로 기반 세포 리프로그래밍 방법 및 이를 위한 플랫폼, 2023
- DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY, 2020
- 다중 범위의 열 자극에 따른 세포의 열 민감도 측정 장치(Device for measuring heat sensitivity of cells in multi-heat treatment), 2018
- BIO FILTER SHEET, 2017
- 세포 융합 장치 및 세포 융합 방법(Device and method for cell pairing and fusion), 2016
- 미소입자의 자기 배열을 위한 장치 및 방법(Device and method for a high-throughput self-assembly of micro particles in microfluidic channel), 2016
- 미소입자의 변형성 및 피로 특성 분석 장치(Device for analyzing deformability and fatigue characteristic of particles), 2016
- Cell fusion device and cell fusion method, 2015
- Particle arranging device and method, 2015
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Citation and Awards